Restoring the impaired cardiac calcium homeostasis and cardiac function in iron overload rats by the combined deferiprone and N-acetyl cysteine

• Main Authors: Suwakon Wongjaikam, Sirinart Kumfu, Juthamas Khamseekaew, Siriporn C. Chattipakorn, Nipon Chattipakorn
• Format: Journal
• Published: 2018
• Subjects: Multidisciplinary
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85015344218&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/57982
• Institution: Chiang Mai University

© 2017 The Author(s). Intracellular calcium [Ca2+] i dysregulation plays an important role in the pathophysiology of iron overload cardiomyopathy. Although either iron chelators or antioxidants provide cardioprotection, a comparison of the efficacy of deferoxamine (DFO), deferiprone (DFP), deferasir...