γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199

Two new γ-lactones, eutypellins A (1) and B (2), and two ent-eudesmane sesquiterpenes, ent-4(15)-eudesmen-11-ol-1-one (3) and ent-4(15)-eudesmen-1α,11-diol (4), together with three known pimarane diterpenes, diaporthein B, scopararane A, and libertellenone C, were isolated from the endophytic fungus...

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Main Authors: Isaka M., Palasarn S., Lapanun S., Chanthaket R., Boonyuen N., Lumyong S.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-70349479408&partnerID=40&md5=9dfe3959c27c4707a95378c663292cfe
http://cmuir.cmu.ac.th/handle/6653943832/5803
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-58032014-08-30T03:23:29Z γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199 Isaka M. Palasarn S. Lapanun S. Chanthaket R. Boonyuen N. Lumyong S. Two new γ-lactones, eutypellins A (1) and B (2), and two ent-eudesmane sesquiterpenes, ent-4(15)-eudesmen-11-ol-1-one (3) and ent-4(15)-eudesmen-1α,11-diol (4), together with three known pimarane diterpenes, diaporthein B, scopararane A, and libertellenone C, were isolated from the endophytic fungus Eutypella sp. BCC 13199. The structures of these compounds were elucidated by interpretation of spectroscopic data. The absolute configuration of 4 was confirmed by application of the modified Mosher's method. Eutypellin A (1) and sesquiterpene 3 exhibited weak cytotoxic activities. © 2009 American Chemical Society and American Society of Pharmacognosy. 2014-08-30T03:23:29Z 2014-08-30T03:23:29Z 2009 Article 01633864 10.1021/np900316x 19739600 JNPRD http://www.scopus.com/inward/record.url?eid=2-s2.0-70349479408&partnerID=40&md5=9dfe3959c27c4707a95378c663292cfe http://cmuir.cmu.ac.th/handle/6653943832/5803 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description Two new γ-lactones, eutypellins A (1) and B (2), and two ent-eudesmane sesquiterpenes, ent-4(15)-eudesmen-11-ol-1-one (3) and ent-4(15)-eudesmen-1α,11-diol (4), together with three known pimarane diterpenes, diaporthein B, scopararane A, and libertellenone C, were isolated from the endophytic fungus Eutypella sp. BCC 13199. The structures of these compounds were elucidated by interpretation of spectroscopic data. The absolute configuration of 4 was confirmed by application of the modified Mosher's method. Eutypellin A (1) and sesquiterpene 3 exhibited weak cytotoxic activities. © 2009 American Chemical Society and American Society of Pharmacognosy.
format Article
author Isaka M.
Palasarn S.
Lapanun S.
Chanthaket R.
Boonyuen N.
Lumyong S.
spellingShingle Isaka M.
Palasarn S.
Lapanun S.
Chanthaket R.
Boonyuen N.
Lumyong S.
γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199
author_facet Isaka M.
Palasarn S.
Lapanun S.
Chanthaket R.
Boonyuen N.
Lumyong S.
author_sort Isaka M.
title γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199
title_short γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199
title_full γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199
title_fullStr γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199
title_full_unstemmed γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199
title_sort γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus eutypella sp. bcc 13199
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-70349479408&partnerID=40&md5=9dfe3959c27c4707a95378c663292cfe
http://cmuir.cmu.ac.th/handle/6653943832/5803
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