Dipeptidyl peptidase-4 inhibitor enhances restoration of salivary glands impaired by obese-insulin resistance

• Main Authors: Jitjiroj Ittichaicharoen, Nattayaporn Apaijai, Pongpan Tanajak, Piangkwan Sa-nguanmoo, Nipon Chattipakorn, Siriporn Chattipakorn
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Dentistry; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85031920896&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/58317
• Institution: Chiang Mai University

© 2017 Elsevier Ltd Objective Chronic high-fat diet consumption causes not only obese- insulin resistance, but also leads to pathological changes in salivary glands, including increased mitochondrial dysfunction, apoptosis, oxidative stress, and inflammation. Dipeptidyl peptidase-4 inhibitor (vildag...