Hypoglycemic activity and acute toxicity of human insulin-tat mixture

• Main Authors: Aranya Manosroi, Chanutchamon Sutthiwanjampa, Worapaka Manosroi, Rolf G. Werner, Friedrich Göz, Theeraphong Tangjai, Worapong Kitdamrongtham, Jiradej Manosroi
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Materials Science; Mathematics; Physics and Astronomy
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85040939589&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/58344
• Institution: Chiang Mai University

© 2018, Chiang Mai University. All rights reserved. When orally administered in fasted alloxan-induced diabetic mice, human insulin mixed with the cell penetrating peptides, the trans-activator of transcription (Tat) gave the hypoglycemic activity, while mixed with the VP1-BC loop polioviral capsid...