Towards controlling the crystallisation behaviour of fenofibrate melt: Triggers of crystallisation and polymorphic transformation

• المؤلفون الرئيسيون: Pratchaya Tipduangta, Khaled Takieddin, László Fábián, Peter Belton, Sheng Qi
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Chemical Engineering; Chemistry
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85045526216&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/58422
• المؤسسة: Chiang Mai University

© 2018 The Royal Society of Chemistry. Fenofibrate (FEN) is a dyslipidemia treatment agent which is poorly soluble in water. FEN has tendency to form polymorphs and its crystallisation behaviour is difficult to predict. The nucleation process can be initiated by mechanical disruption such as ball mi...