Silicon photonic resonator for label-free bio-sensing application
© 2018 SPIE. In medical diagnostics there is an increasing demand for biosensors that can specifically detect biological analytes in a fluid. Especially label-free sensing, consistings of a transducer with biorecognition molecules immobilized on its surface without relying on fluorescent dye. In thi...
Saved in:
Main Authors: | , , , , , , |
---|---|
Format: | Conference Proceeding |
Published: |
2018
|
Subjects: | |
Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85047328513&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/58584 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Chiang Mai University |
id |
th-cmuir.6653943832-58584 |
---|---|
record_format |
dspace |
spelling |
th-cmuir.6653943832-585842018-09-05T04:39:43Z Silicon photonic resonator for label-free bio-sensing application Suruk Udomsom Ukrit Mankong Nipon Theera-Umpon Nattapol Ittipratheep Toshimasa Umezawa Atsushi Matsumoto Naokatsu Yamamoto Computer Science Engineering Materials Science Mathematics Physics and Astronomy © 2018 SPIE. In medical diagnostics there is an increasing demand for biosensors that can specifically detect biological analytes in a fluid. Especially label-free sensing, consistings of a transducer with biorecognition molecules immobilized on its surface without relying on fluorescent dye. In this paper we study the design and fabrication of a silicon nanowire photonic ring resonator and its feasibility as a biosensor. We have simulated and fabricated racetrack ring resonators which have a few tenths of micrometer gap, up to 0.5 μm between the input / output waveguides and the resonators. It is found that the devices can be designed with large Q factors. Sensitivity to biomaterial detection has been simulated for antibody (goat anti-mouse IgG) - antigen (mouse IgG) using 3-dimensional Finite Difference Time Domain technique. The simulated results show that the ring resonator has a response 15 nm resonance shift per refractive index unit. Antibody coating method is also discussed in this paper which can be applied to other antibody-antigen types. 2018-09-05T04:26:31Z 2018-09-05T04:26:31Z 2018-01-01 Conference Proceeding 1996756X 0277786X 2-s2.0-85047328513 10.1117/12.2300961 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85047328513&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/58584 |
institution |
Chiang Mai University |
building |
Chiang Mai University Library |
country |
Thailand |
collection |
CMU Intellectual Repository |
topic |
Computer Science Engineering Materials Science Mathematics Physics and Astronomy |
spellingShingle |
Computer Science Engineering Materials Science Mathematics Physics and Astronomy Suruk Udomsom Ukrit Mankong Nipon Theera-Umpon Nattapol Ittipratheep Toshimasa Umezawa Atsushi Matsumoto Naokatsu Yamamoto Silicon photonic resonator for label-free bio-sensing application |
description |
© 2018 SPIE. In medical diagnostics there is an increasing demand for biosensors that can specifically detect biological analytes in a fluid. Especially label-free sensing, consistings of a transducer with biorecognition molecules immobilized on its surface without relying on fluorescent dye. In this paper we study the design and fabrication of a silicon nanowire photonic ring resonator and its feasibility as a biosensor. We have simulated and fabricated racetrack ring resonators which have a few tenths of micrometer gap, up to 0.5 μm between the input / output waveguides and the resonators. It is found that the devices can be designed with large Q factors. Sensitivity to biomaterial detection has been simulated for antibody (goat anti-mouse IgG) - antigen (mouse IgG) using 3-dimensional Finite Difference Time Domain technique. The simulated results show that the ring resonator has a response 15 nm resonance shift per refractive index unit. Antibody coating method is also discussed in this paper which can be applied to other antibody-antigen types. |
format |
Conference Proceeding |
author |
Suruk Udomsom Ukrit Mankong Nipon Theera-Umpon Nattapol Ittipratheep Toshimasa Umezawa Atsushi Matsumoto Naokatsu Yamamoto |
author_facet |
Suruk Udomsom Ukrit Mankong Nipon Theera-Umpon Nattapol Ittipratheep Toshimasa Umezawa Atsushi Matsumoto Naokatsu Yamamoto |
author_sort |
Suruk Udomsom |
title |
Silicon photonic resonator for label-free bio-sensing application |
title_short |
Silicon photonic resonator for label-free bio-sensing application |
title_full |
Silicon photonic resonator for label-free bio-sensing application |
title_fullStr |
Silicon photonic resonator for label-free bio-sensing application |
title_full_unstemmed |
Silicon photonic resonator for label-free bio-sensing application |
title_sort |
silicon photonic resonator for label-free bio-sensing application |
publishDate |
2018 |
url |
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85047328513&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/58584 |
_version_ |
1681425092741955584 |