Silicon photonic resonator for label-free bio-sensing application

© 2018 SPIE. In medical diagnostics there is an increasing demand for biosensors that can specifically detect biological analytes in a fluid. Especially label-free sensing, consistings of a transducer with biorecognition molecules immobilized on its surface without relying on fluorescent dye. In thi...

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Main Authors: Suruk Udomsom, Ukrit Mankong, Nipon Theera-Umpon, Nattapol Ittipratheep, Toshimasa Umezawa, Atsushi Matsumoto, Naokatsu Yamamoto
Format: Conference Proceeding
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/58584
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-585842018-09-05T04:39:43Z Silicon photonic resonator for label-free bio-sensing application Suruk Udomsom Ukrit Mankong Nipon Theera-Umpon Nattapol Ittipratheep Toshimasa Umezawa Atsushi Matsumoto Naokatsu Yamamoto Computer Science Engineering Materials Science Mathematics Physics and Astronomy © 2018 SPIE. In medical diagnostics there is an increasing demand for biosensors that can specifically detect biological analytes in a fluid. Especially label-free sensing, consistings of a transducer with biorecognition molecules immobilized on its surface without relying on fluorescent dye. In this paper we study the design and fabrication of a silicon nanowire photonic ring resonator and its feasibility as a biosensor. We have simulated and fabricated racetrack ring resonators which have a few tenths of micrometer gap, up to 0.5 μm between the input / output waveguides and the resonators. It is found that the devices can be designed with large Q factors. Sensitivity to biomaterial detection has been simulated for antibody (goat anti-mouse IgG) - antigen (mouse IgG) using 3-dimensional Finite Difference Time Domain technique. The simulated results show that the ring resonator has a response 15 nm resonance shift per refractive index unit. Antibody coating method is also discussed in this paper which can be applied to other antibody-antigen types. 2018-09-05T04:26:31Z 2018-09-05T04:26:31Z 2018-01-01 Conference Proceeding 1996756X 0277786X 2-s2.0-85047328513 10.1117/12.2300961 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85047328513&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/58584
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Computer Science
Engineering
Materials Science
Mathematics
Physics and Astronomy
spellingShingle Computer Science
Engineering
Materials Science
Mathematics
Physics and Astronomy
Suruk Udomsom
Ukrit Mankong
Nipon Theera-Umpon
Nattapol Ittipratheep
Toshimasa Umezawa
Atsushi Matsumoto
Naokatsu Yamamoto
Silicon photonic resonator for label-free bio-sensing application
description © 2018 SPIE. In medical diagnostics there is an increasing demand for biosensors that can specifically detect biological analytes in a fluid. Especially label-free sensing, consistings of a transducer with biorecognition molecules immobilized on its surface without relying on fluorescent dye. In this paper we study the design and fabrication of a silicon nanowire photonic ring resonator and its feasibility as a biosensor. We have simulated and fabricated racetrack ring resonators which have a few tenths of micrometer gap, up to 0.5 μm between the input / output waveguides and the resonators. It is found that the devices can be designed with large Q factors. Sensitivity to biomaterial detection has been simulated for antibody (goat anti-mouse IgG) - antigen (mouse IgG) using 3-dimensional Finite Difference Time Domain technique. The simulated results show that the ring resonator has a response 15 nm resonance shift per refractive index unit. Antibody coating method is also discussed in this paper which can be applied to other antibody-antigen types.
format Conference Proceeding
author Suruk Udomsom
Ukrit Mankong
Nipon Theera-Umpon
Nattapol Ittipratheep
Toshimasa Umezawa
Atsushi Matsumoto
Naokatsu Yamamoto
author_facet Suruk Udomsom
Ukrit Mankong
Nipon Theera-Umpon
Nattapol Ittipratheep
Toshimasa Umezawa
Atsushi Matsumoto
Naokatsu Yamamoto
author_sort Suruk Udomsom
title Silicon photonic resonator for label-free bio-sensing application
title_short Silicon photonic resonator for label-free bio-sensing application
title_full Silicon photonic resonator for label-free bio-sensing application
title_fullStr Silicon photonic resonator for label-free bio-sensing application
title_full_unstemmed Silicon photonic resonator for label-free bio-sensing application
title_sort silicon photonic resonator for label-free bio-sensing application
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85047328513&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/58584
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