Investigation of associations between exposures to pesticides and testosterone levels in Thai farmers

© 2018, © 2018 Taylor & Francis. We conducted a cross-sectional study to assess the relationship between pesticide exposures and testosterone levels in 133 male Thai farmers. Urine and serum samples were collected concurrently from participants. Urine was analyzed for levels of specific and no...

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Main Authors: Parinya Panuwet, Chandresh Ladva, Dana Boyd Barr, Tippawan Prapamontol, John D. Meeker, Priya Esilda D'Souza, Héctor Maldonado, P. Barry Ryan, Mark G. Robson
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/58726
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-587262018-09-05T04:37:58Z Investigation of associations between exposures to pesticides and testosterone levels in Thai farmers Parinya Panuwet Chandresh Ladva Dana Boyd Barr Tippawan Prapamontol John D. Meeker Priya Esilda D'Souza Héctor Maldonado P. Barry Ryan Mark G. Robson Environmental Science Medicine Pharmacology, Toxicology and Pharmaceutics © 2018, © 2018 Taylor & Francis. We conducted a cross-sectional study to assess the relationship between pesticide exposures and testosterone levels in 133 male Thai farmers. Urine and serum samples were collected concurrently from participants. Urine was analyzed for levels of specific and nonspecific metabolites of organophosphates (OPs), pyrethroids, select herbicides, and fungicides. Serum was analyzed for total and free testosterone. Linear regression analyses revealed significant negative relationships between total testosterone and the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) after controlling for covariates (eg, age, BMI, smoking status). Positive significant associations were found between some OP pesticides and total testosterone. Due to the small sample size and the observational nature of the study, future investigation is needed to confirm our results and to elucidate the biological mechanisms. 2018-09-05T04:29:30Z 2018-09-05T04:29:30Z 2018-07-04 Journal 21544700 19338244 2-s2.0-85030674180 10.1080/19338244.2017.1378606 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85030674180&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/58726
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Environmental Science
Medicine
Pharmacology, Toxicology and Pharmaceutics
spellingShingle Environmental Science
Medicine
Pharmacology, Toxicology and Pharmaceutics
Parinya Panuwet
Chandresh Ladva
Dana Boyd Barr
Tippawan Prapamontol
John D. Meeker
Priya Esilda D'Souza
Héctor Maldonado
P. Barry Ryan
Mark G. Robson
Investigation of associations between exposures to pesticides and testosterone levels in Thai farmers
description © 2018, © 2018 Taylor & Francis. We conducted a cross-sectional study to assess the relationship between pesticide exposures and testosterone levels in 133 male Thai farmers. Urine and serum samples were collected concurrently from participants. Urine was analyzed for levels of specific and nonspecific metabolites of organophosphates (OPs), pyrethroids, select herbicides, and fungicides. Serum was analyzed for total and free testosterone. Linear regression analyses revealed significant negative relationships between total testosterone and the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) after controlling for covariates (eg, age, BMI, smoking status). Positive significant associations were found between some OP pesticides and total testosterone. Due to the small sample size and the observational nature of the study, future investigation is needed to confirm our results and to elucidate the biological mechanisms.
format Journal
author Parinya Panuwet
Chandresh Ladva
Dana Boyd Barr
Tippawan Prapamontol
John D. Meeker
Priya Esilda D'Souza
Héctor Maldonado
P. Barry Ryan
Mark G. Robson
author_facet Parinya Panuwet
Chandresh Ladva
Dana Boyd Barr
Tippawan Prapamontol
John D. Meeker
Priya Esilda D'Souza
Héctor Maldonado
P. Barry Ryan
Mark G. Robson
author_sort Parinya Panuwet
title Investigation of associations between exposures to pesticides and testosterone levels in Thai farmers
title_short Investigation of associations between exposures to pesticides and testosterone levels in Thai farmers
title_full Investigation of associations between exposures to pesticides and testosterone levels in Thai farmers
title_fullStr Investigation of associations between exposures to pesticides and testosterone levels in Thai farmers
title_full_unstemmed Investigation of associations between exposures to pesticides and testosterone levels in Thai farmers
title_sort investigation of associations between exposures to pesticides and testosterone levels in thai farmers
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85030674180&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/58726
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