A significant mechanism of molecular recognition between bioflavonoids and P-glycoprotein leading to herb-drug interactions

• Main Authors: Pathomwat Wongrattanakamon, Piyarat Nimmanpipug, Busaban Sirithunyalug, Sunee Chansakaow, Supat Jiranusornkul
• Format: Journal
• Published: 2018
• Subjects: Environmental Science; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85025825699&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/58743
• Institution: Chiang Mai University

© 2017 Informa UK Limited, trading as Taylor & Francis Group. Inhibition of P-glycoprotein (P-gp)’s function may conduct significant changes in the prescription drugs’ pharmacokinetic profiles and escalate potential risks in taking place of drug/herb-drug interactions. Computational modeling w...