Dynamic 2D self-phase-map Nyquist ghost correction for simultaneous multi-slice echo planar imaging

© 2018 International Society for Magnetic Resonance in Medicine Purpose: To develop a reconstruction pipeline that intrinsically accounts for both simultaneous multislice echo planar imaging (SMS-EPI) reconstruction and dynamic slice-specific Nyquist ghosting correction in time-series data. Methods:...

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Bibliographic Details
Main Authors: Uten Yarach, Yi Hang Tung, Kawin Setsompop, Myung Ho In, Itthi Chatnuntawech, Renat Yakupov, Frank Godenschweger, Oliver Speck
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85041515586&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/58844
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Institution: Chiang Mai University
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Summary:© 2018 International Society for Magnetic Resonance in Medicine Purpose: To develop a reconstruction pipeline that intrinsically accounts for both simultaneous multislice echo planar imaging (SMS-EPI) reconstruction and dynamic slice-specific Nyquist ghosting correction in time-series data. Methods: After 1D slice-group average phase correction, the separate polarity (i.e., even and odd echoes) SMS-EPI data were unaliased by slice GeneRalized Autocalibrating Partial Parallel Acquisition. Both the slice-unaliased even and odd echoes were jointly reconstructed using a model-based framework, extended for SMS-EPI reconstruction that estimates a 2D self-phase map, corrects dynamic slice-specific phase errors, and combines data from all coils and echoes to obtain the final images. Results: The percentage ghost-to-signal ratios (%GSRs) and its temporal variations for MB3Ry2 with a field of view/4 shift in a human brain obtained by the proposed dynamic 2D and standard 1D phase corrections were 1.37 ± 0.11 and 2.66 ± 0.16, respectively. Even with a large regularization parameter λ applied in the proposed reconstruction, the smoothing effect in fMRI activation maps was comparable to a very small Gaussian kernel size 1 × 1 × 1 mm3. Conclusion: The proposed reconstruction pipeline reduced slice-specific phase errors in SMS-EPI, resulting in reduction of GSR. It is applicable for functional MRI studies because the smoothing effect caused by the regularization parameter selection can be minimal in a blood-oxygen-level–dependent activation map.