Differential expression of Lp-PLA2 in obesity and type 2 diabetes and the influence of lipids

• Main Authors: Laura Jackisch, Warunee Kumsaiyai, Jonathan D. Moore, Nasser Al-Daghri, Ioannis Kyrou, Thomas M. Barber, Harpal Randeva, Sudhesh Kumar, Gyanendra Tripathi, Philip G. McTernan
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85041861418&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/58935
• Institution: Chiang Mai University

© 2018, The Author(s). Aims/hypothesis: Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a circulatory macrophage-derived factor that increases with obesity and leads to a higher risk of cardiovascular disease (CVD). Despite this, its role in adipose tissue and the adipocyte is unknown. Therefor...