Submacular hemorrhage: Visual outcomes and prognostic factors

• Main Authors: Paradee Kunavisarut, Tipparut Thithuan, Direk Patikulsila, Janejit Choovuthayakorn, Nawat Watanachai, Voraporn Chaikitmongkol, Kessara Pathanapitoon, Aniki Rothova
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85046273854&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/58970
• Institution: Chiang Mai University

Copyright © 2017 Asia-Pacific Academy of Ophthalmology. Unauthorized reproduction of this article is prohibited. Purpose: To describe causes, visual outcomes, and prognostic factors in patients with submacular hemorrhage (SMH). Design: Retrospective case review. Methods: We performed a retrospective review of SMH with a size of at least 1 disc diameter. SMH causes were classified into 3 groups: 1) neovascular age-related macular degeneration (nAMD), 2) polypoidal choroidal vasculopathy (PCV), and 3) other miscellaneous causes. Results: Ninety-eight eyes of 98 patients were included. Based on clinical presentation and indocyanine green angiography (iCGA), the diagnoses of PCV (59%), nAMD (31%), and miscellaneous other causes (10%) were made. PCV patients were younger (P = 0.005) and had larger SMH size than nAMD patients (P = 0.008). Poor visual outcome [>1.0 logarithm of the minimum angle of resolution (logMAR)] at 6 months was associated with low initial visual acuity (VA; >1.0 logMAR; P = 0.002) and with the diagnosis of nAMD (P = 0.02). in addition, limited visual outcomes were noted for patients older than 65 years and those with persistent SMH for at least 2 months. Conclusions: PCV was the most common cause of SMH in Thailand. iCGA represented a valuable tool for the diagnosis. Visual outcomes were limited for patients with nAMD and for patients who presented with poor initial VA.