Analysis of HLA-B Allelic Variation and IFN-γ ELISpot Responses in Patients with Severe Cutaneous Adverse Reactions Associated with Drugs

• Main Authors: Jettanong Klaewsongkram, Chonlaphat Sukasem, Pattarawat Thantiworasit, Nithikan Suthumchai, Pawinee Rerknimitr, Papapit Tuchinda, Leena Chularojanamontri, Yuttana Srinoulprasert, Ticha Rerkpattanapipat, Kumutnart Chanprapaph, Wareeporn Disphanurat, Panlop Chakkavittumrong, Napatra Tovanabutra, Chutika Srisuttiyakorn
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85048935205&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/59056
• Institution: Chiang Mai University

© 2018 American Academy of Allergy, Asthma & Immunology Background: The prevention and confirmation of drug-induced severe cutaneous adverse reactions (SCARs) are difficult. Objective: To determine the benefit of HLA-B allele prescreening and the measurement of drug-specific IFN-γ-releasing ce...