Use of Potentially Inappropriate Medications in People With Dementia in Vietnam and Its Associated Factors

• Main Authors: Tuan Anh Nguyen, Thang Pham, Huyen Thi Thanh Vu, Thanh Xuan Nguyen, Trinh Thi Vu, Binh Thi Thanh Nguyen, Ngoc Quynh Nguyen, Binh Thanh Nguyen, Tam Ngoc Nguyen, Sinh Viet Phan, Anh Trung Nguyen, Tuan Le Pham, Ha Thu Dang, Lisa Kalisch-Ellett, Marianne Gillam, Nicole Pratt, Sun Qiang, Haipeng Wang, Tipaporn Kanjanarach, Mohamed Azmi Ahmad Hassali, Zaheer Ud Din Babar, Asrenee Ab Razak, Dujrudee Chinwong, Elizabeth E. Roughead
• Format: Journal
• Published: 2018
• Subjects: Medicine; Neuroscience; Psychology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85045271531&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/59059
• Institution: Chiang Mai University

© 2018, The Author(s) 2018. This study examined the use of potentially inappropriate medicines that may affect cognition (PIMcog) in people with dementia and its associated factors. Medical records of all outpatients with dementia attending a tertiary hospital in Vietnam between January 1, 2015, and December 31, 2016, were examined. Medicine use was assessed against a list of PIMcog. Variables associated with having a PIMcog were assessed using a multiple logistic regression. Of the 128 patients, 41% used a PIMcog, 39.1% used cholinesterase inhibitors (CEIs) concomitantly with anticholinergics, and 18% used antipsychotics. The number of hospital visits (adjusted odds ratio [OR]: 1.08; 95% confidence interval [CI]: 1.02-1.16) and number of treating specialists (adjusted OR: 0.61; 95% CI: 0.45-0.83) were associated with PIMcog use. This study highlights a high-level use of medicines that can further impair cognition or reduce the effectiveness of CEIs in people with dementia. Efforts to improve quality use of medicines for this population are warranted.