Association of the S267F variant on NTCP gene and treatment response to pegylated interferon in patients with chronic hepatitis B: A multicentre study

• Main Authors: Kessarin Thanapirom, Sirinporn Suksawatamnuay, Wattana Sukeepaisarnjaroen, Sombat Treeprasertsuk, Tawesak Tanwandee, Phunchai Charatcharoenwitthaya, Satawat Thongsawat, Apinya Leerapun, Teerha Piratvisuth, Rattana Boonsirichan, Chalermrat Bunchorntavakul, Chaowalit Pattanasirigool, Bubpha Pornthisarn, Supoj Tuntipanichteerakul, Ekawee Sripariwuth, Woramon Jeamsripong, Theeranun Sanpajit, Yong Poovorawan, Piyawat Komolmit
• 格式: 雜誌
• 出版: 2018
• 主題: Medicine; Pharmacology, Toxicology and Pharmaceutics
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85042943989&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/59064
• 機構: Chiang Mai University

©2018 International Medical Press. Background: Sodium taurocholate co-Transporting polypeptide (NTCP) is a cell receptor for HBV. The S267F variant on the NTCP gene is inversely associated with the chronicity of HBV infection, progression to cirrhosis and hepatocellular carcinoma in East Asian popul...