An in vitro potency assay using nicotinic acetylcholine receptor binding works well with antivenoms against Bungarus candidus and Naja naja

• Main Authors: Kavi Ratanabanangkoon, Pavinee Simsiriwong, Kritsada Pruksaphon, Kae Yi Tan, Bunkuea Chantrathonkul, Sukanya Eursakun, Choo Hock Tan
• Format: Journal
• Published: 2018
• Subjects: Multidisciplinary
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85049173470&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/59191
• Institution: Chiang Mai University

© 2018 The Author(s). In order to facilitate/expedite the production of effective and affordable snake antivenoms, a novel in vitro potency assay was previously developed. The assay is based on an antiserum's ability to bind to postsynaptic neurotoxin (PSNT) and thereby inhibit the PSNT binding...