γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199

Two new γ-lactones, eutypellins A (1) and B (2), and two ent-eudesmane sesquiterpenes, ent-4(15)-eudesmen-11-ol-1-one (3) and ent-4(15)-eudesmen-1α,11-diol (4), together with three known pimarane diterpenes, diaporthein B, scopararane A, and libertellenone C, were isolated from the endophytic fungus...

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Main Authors:	Masahiko Isaka, Somporn Palasarn, Sanisa Lapanun, Rungtiwa Chanthaket, Nattawut Boonyuen, Saisamorn Lumyong
Format:	Journal
Published:	2018
Subjects:	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70349479408&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/59342
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Institution:	Chiang Mai University

id	th-cmuir.6653943832-59342
record_format	dspace
spelling	th-cmuir.6653943832-593422018-09-10T03:23:51Z γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199 Masahiko Isaka Somporn Palasarn Sanisa Lapanun Rungtiwa Chanthaket Nattawut Boonyuen Saisamorn Lumyong Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics Two new γ-lactones, eutypellins A (1) and B (2), and two ent-eudesmane sesquiterpenes, ent-4(15)-eudesmen-11-ol-1-one (3) and ent-4(15)-eudesmen-1α,11-diol (4), together with three known pimarane diterpenes, diaporthein B, scopararane A, and libertellenone C, were isolated from the endophytic fungus Eutypella sp. BCC 13199. The structures of these compounds were elucidated by interpretation of spectroscopic data. The absolute configuration of 4 was confirmed by application of the modified Mosher's method. Eutypellin A (1) and sesquiterpene 3 exhibited weak cytotoxic activities. © 2009 American Chemical Society and American Society of Pharmacognosy. 2018-09-10T03:14:04Z 2018-09-10T03:14:04Z 2009-09-25 Journal 01633864 2-s2.0-70349479408 10.1021/np900316x https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70349479408&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/59342
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
topic	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics
spellingShingle	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics Masahiko Isaka Somporn Palasarn Sanisa Lapanun Rungtiwa Chanthaket Nattawut Boonyuen Saisamorn Lumyong γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199
description	Two new γ-lactones, eutypellins A (1) and B (2), and two ent-eudesmane sesquiterpenes, ent-4(15)-eudesmen-11-ol-1-one (3) and ent-4(15)-eudesmen-1α,11-diol (4), together with three known pimarane diterpenes, diaporthein B, scopararane A, and libertellenone C, were isolated from the endophytic fungus Eutypella sp. BCC 13199. The structures of these compounds were elucidated by interpretation of spectroscopic data. The absolute configuration of 4 was confirmed by application of the modified Mosher's method. Eutypellin A (1) and sesquiterpene 3 exhibited weak cytotoxic activities. © 2009 American Chemical Society and American Society of Pharmacognosy.
format	Journal
author	Masahiko Isaka Somporn Palasarn Sanisa Lapanun Rungtiwa Chanthaket Nattawut Boonyuen Saisamorn Lumyong
author_facet	Masahiko Isaka Somporn Palasarn Sanisa Lapanun Rungtiwa Chanthaket Nattawut Boonyuen Saisamorn Lumyong
author_sort	Masahiko Isaka
title	γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199
title_short	γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199
title_full	γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199
title_fullStr	γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199
title_full_unstemmed	γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199
title_sort	γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus eutypella sp. bcc 13199
publishDate	2018
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70349479408&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/59342
_version_	1681425233454563328

γ-lactones and ent-eudesmane sesquiterpenes from the endophytic fungus Eutypella sp. BCC 13199

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