Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species

• Main Authors: Supachai Yodkeeree, Bokyung Sung, Pornngarm Limtrakul, Bharat B. Aggarwal
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=69249083578&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/59351
• Institution: Chiang Mai University

Identification of the active component and mechanisms of action of traditional medicines is highly desirable. We investigated whether zerumbone, a sesquiterpene from tropical ginger, can enhance the anticancer effects of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). We found that...