Syntheses of methylenolactocin and nephrosterinic acid via diastereoselective acylation and chemoselective reduction-lactonization

• Main Authors: Rattana Jongkol, Ruangrat Choommongkol, Bongkoch Tarnchompoo, Piyarat Nimmanpipug, Puttinan Meepowpan
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=67649840195&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/59353
• Institution: Chiang Mai University

The syntheses of methylenolactocin, nephrosterinic acid and their derivatives can be achieved by using the efficient diastereoselective acylation of dimethyl itaconate-anthracene adduct followed by tandem chemoselective reduction-lactonization. © 2009 Elsevier Ltd. All rights reserved.