Age-related changes of the concentrations of select elements in the prostates of Japanese

To elucidate compositional changes of the prostate with aging, the authors investigated age-related changes of elements in the prostates and the relationships among their elements using Japanese and Thai. After ordinary dissections by students at Nara Medical University and Chiang Mai University wer...

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Main Authors: Setsuko Tohno, Masato Kobayashi, Hayato Shimizu, Yoshiyuki Tohno, Patipath Suwannahoy, Cho Azuma, Takeshi Minami, Apichat Sinthubua, Pasuk Mahakkanukrauh
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/59389
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-593892018-09-10T03:22:42Z Age-related changes of the concentrations of select elements in the prostates of Japanese Setsuko Tohno Masato Kobayashi Hayato Shimizu Yoshiyuki Tohno Patipath Suwannahoy Cho Azuma Takeshi Minami Apichat Sinthubua Pasuk Mahakkanukrauh Biochemistry, Genetics and Molecular Biology Chemistry Medicine To elucidate compositional changes of the prostate with aging, the authors investigated age-related changes of elements in the prostates and the relationships among their elements using Japanese and Thai. After ordinary dissections by students at Nara Medical University and Chiang Mai University were finished, the prostates were resected from the subjects. Fifty-seven Japanese subjects ranged in age from 65 to 101 years (average age=82.5±7.8 years), whereas 13 Thai subjects ranged in age from 43 to 86 years (average age=67.9±11.9 years). After ashing with nitric acid and perchloric acid, element contents were determined by inductively coupled plasma-atomic emission spectrometry. It was found that although there were no significant correlations between age and seven element contents, such as Ca, P, S, Mg, Zn, Fe, and Na, in the prostates of Japanese, high contents of Ca (>5 mg/g) and P (>4 mg/g) were contained in one fourth of the prostates of Japanese over 70 years of age. In the prostates of Thai, a significant direct correlation was found between age and Ca content, but it was not found between age and the other element contents, such as P, S, Mg, Zn, Fe, and Na. Regarding the relationships among their elements, extremely significant direct correlations were found among the contents of Ca, P, Mg, Zn, and Na in the prostates of Japanese. In the prostates of Thai, significant direct correlations were found among the contents of Ca, Mg, and Zn, but no significant correlations were found between Ca and P contents and between P and Mg contents. Regarding the relationships among their elements, there were differences between the prostates of Japanese and Thai. To examine whether element contents changed in prostatic hypertrophy, the transverse width of the Japanese prostates was measured. No significant correlations were found between the transverse width and element contents, such as Ca, P, S, Mg, Zn, Fe, and Na, in the Japanese prostates. Therefore, it is unlikely that the increase of elements results in prostatic hypertrophy. © 2008 Humana Press Inc. 2018-09-10T03:14:37Z 2018-09-10T03:14:37Z 2009-03-01 Journal 01634984 2-s2.0-63649156901 10.1007/s12011-008-8241-5 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=63649156901&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/59389
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Biochemistry, Genetics and Molecular Biology
Chemistry
Medicine
spellingShingle Biochemistry, Genetics and Molecular Biology
Chemistry
Medicine
Setsuko Tohno
Masato Kobayashi
Hayato Shimizu
Yoshiyuki Tohno
Patipath Suwannahoy
Cho Azuma
Takeshi Minami
Apichat Sinthubua
Pasuk Mahakkanukrauh
Age-related changes of the concentrations of select elements in the prostates of Japanese
description To elucidate compositional changes of the prostate with aging, the authors investigated age-related changes of elements in the prostates and the relationships among their elements using Japanese and Thai. After ordinary dissections by students at Nara Medical University and Chiang Mai University were finished, the prostates were resected from the subjects. Fifty-seven Japanese subjects ranged in age from 65 to 101 years (average age=82.5±7.8 years), whereas 13 Thai subjects ranged in age from 43 to 86 years (average age=67.9±11.9 years). After ashing with nitric acid and perchloric acid, element contents were determined by inductively coupled plasma-atomic emission spectrometry. It was found that although there were no significant correlations between age and seven element contents, such as Ca, P, S, Mg, Zn, Fe, and Na, in the prostates of Japanese, high contents of Ca (>5 mg/g) and P (>4 mg/g) were contained in one fourth of the prostates of Japanese over 70 years of age. In the prostates of Thai, a significant direct correlation was found between age and Ca content, but it was not found between age and the other element contents, such as P, S, Mg, Zn, Fe, and Na. Regarding the relationships among their elements, extremely significant direct correlations were found among the contents of Ca, P, Mg, Zn, and Na in the prostates of Japanese. In the prostates of Thai, significant direct correlations were found among the contents of Ca, Mg, and Zn, but no significant correlations were found between Ca and P contents and between P and Mg contents. Regarding the relationships among their elements, there were differences between the prostates of Japanese and Thai. To examine whether element contents changed in prostatic hypertrophy, the transverse width of the Japanese prostates was measured. No significant correlations were found between the transverse width and element contents, such as Ca, P, S, Mg, Zn, Fe, and Na, in the Japanese prostates. Therefore, it is unlikely that the increase of elements results in prostatic hypertrophy. © 2008 Humana Press Inc.
format Journal
author Setsuko Tohno
Masato Kobayashi
Hayato Shimizu
Yoshiyuki Tohno
Patipath Suwannahoy
Cho Azuma
Takeshi Minami
Apichat Sinthubua
Pasuk Mahakkanukrauh
author_facet Setsuko Tohno
Masato Kobayashi
Hayato Shimizu
Yoshiyuki Tohno
Patipath Suwannahoy
Cho Azuma
Takeshi Minami
Apichat Sinthubua
Pasuk Mahakkanukrauh
author_sort Setsuko Tohno
title Age-related changes of the concentrations of select elements in the prostates of Japanese
title_short Age-related changes of the concentrations of select elements in the prostates of Japanese
title_full Age-related changes of the concentrations of select elements in the prostates of Japanese
title_fullStr Age-related changes of the concentrations of select elements in the prostates of Japanese
title_full_unstemmed Age-related changes of the concentrations of select elements in the prostates of Japanese
title_sort age-related changes of the concentrations of select elements in the prostates of japanese
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=63649156901&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/59389
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