One-pot synthesis of 3,4-dihydropyrimidine-2-(1H)-ones using CsF-Celite as catalyst

A facile, efficient, and environmentally benign procedure for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones via the cyclocondensation reaction of aromatic aldehyde, ethyl acetoaceate, and urea catalyzed by CsF-Celite was developed. This environmentally friendly method is superior to previous met...

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Bibliographic Details
Main Authors: Sirirat Chancharunee, Pilaiwan Pinhom, Manat Pohmakotr, Patrick Perlmutter
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=61649104632&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/59487
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Institution: Chiang Mai University
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Summary:A facile, efficient, and environmentally benign procedure for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones via the cyclocondensation reaction of aromatic aldehyde, ethyl acetoaceate, and urea catalyzed by CsF-Celite was developed. This environmentally friendly method is superior to previous methods with respect to reaction time, yield, and workup. Copyright © Taylor & Francis Group, LLC.