Broad usage spectrum of G protein-coupled receptors as coreceptors by primary isolates of HIV

• Main Authors: Nobuaki Shimizu, Atsushi Tanaka, Atsushi Oue, Takahisa Mori, Takahiro Ohtsuki, Chatchawann Apichartpiyakul, Hideki Uchiumi, Yoshihisa Nojima, Hiroo Hoshino
• 格式: 雜誌
• 出版: 2018
• 主題: Immunology and Microbiology; Medicine
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=67649668892&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/59639

Objective: HIV-1 can use various G protein-coupled receptors (GPCRs) in addition to CCR5 and CXCR4 as coreceptors;however, this type of HIV-1 infection has hardly been detected in vivo. The objective of this study was to elucidate the spectrum of GPCR usage by HIV-1 populations in vivo. Design: CD4-...