In vitro suppression of the MMP-3 gene in normal and cytokine-treated human chondrosarcoma using small interfering RNA

• المؤلفون الرئيسيون: Korakot Nganvongpanit, Patama Chaochird, Puntita Siengdee, Peraphan Pothacharoen, Kasisin Klunklin, Siriwadee Chomdej, Supamit Mekchay, Prachya Kongtaweelert
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Medicine
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77953665391&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/59754

Background: Matrix metalloproteinase (MMPs) synthesized and secreted from connective tissue cells have been thought to participate in degradation of the extracellular matrix. Increased MMPs activities that degrade proteoglycans have been measured in osteoarthritis cartilage. This study aims to suppr...