Empirical accuracy of fine needle aspiration cytology (FNAC) for preoperative diagnoses of malignant breast lumps in hospitals with restricted health resources

Objective: To reevaluate the additional diagnostic value of FNAC from patient profiles in the diagnosis of breast cancer among patients presenting with breast lumps. Methods: A database was reconstructed from routine follow-up data of patients with breast diseases. Predictive ability of the variable...

Full description

Saved in:
Bibliographic Details
Main Authors: J. Patumanond, T. Kayee, U. Sukkasem
Format: Journal
Published: 2018
Subjects:
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=67649755241&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/59815
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Chiang Mai University
id th-cmuir.6653943832-59815
record_format dspace
spelling th-cmuir.6653943832-598152018-09-10T03:21:55Z Empirical accuracy of fine needle aspiration cytology (FNAC) for preoperative diagnoses of malignant breast lumps in hospitals with restricted health resources J. Patumanond T. Kayee U. Sukkasem Medicine Objective: To reevaluate the additional diagnostic value of FNAC from patient profiles in the diagnosis of breast cancer among patients presenting with breast lumps. Methods: A database was reconstructed from routine follow-up data of patients with breast diseases. Predictive ability of the variables were presented with an area under a receiver operating characteristic (ROC) curve using the logistic model. Results: Age and size of breast lumps alone could predict malignancy with a ROC area of 0.85, (95% CI = 0.81-0.89). When FNAC was added into the logistic model in the presence of age and size of breast lumps, the ROC area increased to 0.95 (95% CI = 0.93-0.97) with statistical significance. Given the same FNAC classification codes, the probability of malignancy increased in older patients and in patients with larger breast lumps. Conclusion: In developing countries where health resources are restricted, FNAC seems to be cost efficient. Continued use of the technique should be encouraged. 2018-09-10T03:21:55Z 2018-09-10T03:21:55Z 2009-07-09 Journal 03922936 2-s2.0-67649755241 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=67649755241&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/59815
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
J. Patumanond
T. Kayee
U. Sukkasem
Empirical accuracy of fine needle aspiration cytology (FNAC) for preoperative diagnoses of malignant breast lumps in hospitals with restricted health resources
description Objective: To reevaluate the additional diagnostic value of FNAC from patient profiles in the diagnosis of breast cancer among patients presenting with breast lumps. Methods: A database was reconstructed from routine follow-up data of patients with breast diseases. Predictive ability of the variables were presented with an area under a receiver operating characteristic (ROC) curve using the logistic model. Results: Age and size of breast lumps alone could predict malignancy with a ROC area of 0.85, (95% CI = 0.81-0.89). When FNAC was added into the logistic model in the presence of age and size of breast lumps, the ROC area increased to 0.95 (95% CI = 0.93-0.97) with statistical significance. Given the same FNAC classification codes, the probability of malignancy increased in older patients and in patients with larger breast lumps. Conclusion: In developing countries where health resources are restricted, FNAC seems to be cost efficient. Continued use of the technique should be encouraged.
format Journal
author J. Patumanond
T. Kayee
U. Sukkasem
author_facet J. Patumanond
T. Kayee
U. Sukkasem
author_sort J. Patumanond
title Empirical accuracy of fine needle aspiration cytology (FNAC) for preoperative diagnoses of malignant breast lumps in hospitals with restricted health resources
title_short Empirical accuracy of fine needle aspiration cytology (FNAC) for preoperative diagnoses of malignant breast lumps in hospitals with restricted health resources
title_full Empirical accuracy of fine needle aspiration cytology (FNAC) for preoperative diagnoses of malignant breast lumps in hospitals with restricted health resources
title_fullStr Empirical accuracy of fine needle aspiration cytology (FNAC) for preoperative diagnoses of malignant breast lumps in hospitals with restricted health resources
title_full_unstemmed Empirical accuracy of fine needle aspiration cytology (FNAC) for preoperative diagnoses of malignant breast lumps in hospitals with restricted health resources
title_sort empirical accuracy of fine needle aspiration cytology (fnac) for preoperative diagnoses of malignant breast lumps in hospitals with restricted health resources
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=67649755241&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/59815
_version_ 1681425321138585600