Transdermal enhancement through rat skin of luciferase plasmid DNA loaded in elastic nanovesicles

• Main Authors: Aranya Manosroi, Narinthorn Khositsuntiwong, Friedrich Gtz, Rolf G. Werner, Jiradej Manosroi
• Format: Journal
• Published: 2018
• Subjects: Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=67650665192&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/59908
• Institution: Chiang Mai University

Transdermal absorption of luciferase plasmid (pLuc) was enhanced by loading in elastic cationic liposomes and niosomes and the application of iontophoresis or the stratum corneum (SC) stripping method. Cationic liposomes (DPPC/Chol/DDAB at a 1:1:1 molar ratio) and niosomes (Tween61/Chol/DDAB at a 1:...