Taxotere, cisplatin, fluorouracil, and leucovorin (TPFL)as induction chemotherapy for locally advanced squamous cell carcinoma of the head and neck.

• Main Authors: Pimkhuan Kamnerdsupaphon, Imjai Chitapanarux, Vicharn Lorvidhaya, Yupa Sumitsawan, Ekkasit Tharavichitkul, Vimol Sukthomya
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=58149214412&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/60141
• Institution: Chiang Mai University

This is a phase II clinical study conducted to evaluate the toxicity and efficacy of a 4-day regimen of docetaxel, cisplatin, fluorouracil, and leucovorin (TPFL) in patients with locoregionally advanced squamous cell carcinoma of the head and neck (SCCHN). PATIENTS AND METHODS: Twenty-one previously...