Ethnobotany and ethnopharmacology of Tabernaemontana divaricata

Tabernaemontana divaricata a common garden plant in tropical countries has been used as a traditional medicine. However, no recent review articles of T. divaricata, particularly discussing its pharmacological properties, are available. This review presents the ethnobotany and ethnopharmacology of T....

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Main Authors: Wasana Pratchayasakul, Anchalee Pongchaidecha, Nipon Chattipakorn, Siriporn Chattipakorn
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/60145
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-601452018-09-10T03:45:51Z Ethnobotany and ethnopharmacology of Tabernaemontana divaricata Wasana Pratchayasakul Anchalee Pongchaidecha Nipon Chattipakorn Siriporn Chattipakorn Biochemistry, Genetics and Molecular Biology Medicine Tabernaemontana divaricata a common garden plant in tropical countries has been used as a traditional medicine. However, no recent review articles of T. divaricata, particularly discussing its pharmacological properties, are available. This review presents the ethnobotany and ethnopharmacology of T. divaricata as well as its potential therapeutic benefits especially of the alkaloidal and non-alkaloidal constituents. Included, are the characteristics of 66 alkaloids isolated and identified from T. divaricata. Non-alkaloids including the enzymes, pyrolytic oil, hydrocarbons, terpenoid and phenolic acids are also documented. Chemotaxonomic aspects of each alkaloid as well as information regarding the pharmacology of crude extracts and individual alkaloids from T. divaricata have been assembled and appraised. The beneficial properties of T. divaricata are antioxidant, anti-infection, anti-tumour action, analgesia and the enhancement of cholinergic activity in both peripheral and central nervous systems. The augmentation of cholinergic function may be of therapeutic benefit for many neurodegenerative diseases, particularly myasthenia gravis and Alzheimer's disease. 2018-09-10T03:38:39Z 2018-09-10T03:38:39Z 2008-09-15 Journal 09715916 09715916 2-s2.0-51349097371 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=51349097371&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/60145
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Biochemistry, Genetics and Molecular Biology
Medicine
spellingShingle Biochemistry, Genetics and Molecular Biology
Medicine
Wasana Pratchayasakul
Anchalee Pongchaidecha
Nipon Chattipakorn
Siriporn Chattipakorn
Ethnobotany and ethnopharmacology of Tabernaemontana divaricata
description Tabernaemontana divaricata a common garden plant in tropical countries has been used as a traditional medicine. However, no recent review articles of T. divaricata, particularly discussing its pharmacological properties, are available. This review presents the ethnobotany and ethnopharmacology of T. divaricata as well as its potential therapeutic benefits especially of the alkaloidal and non-alkaloidal constituents. Included, are the characteristics of 66 alkaloids isolated and identified from T. divaricata. Non-alkaloids including the enzymes, pyrolytic oil, hydrocarbons, terpenoid and phenolic acids are also documented. Chemotaxonomic aspects of each alkaloid as well as information regarding the pharmacology of crude extracts and individual alkaloids from T. divaricata have been assembled and appraised. The beneficial properties of T. divaricata are antioxidant, anti-infection, anti-tumour action, analgesia and the enhancement of cholinergic activity in both peripheral and central nervous systems. The augmentation of cholinergic function may be of therapeutic benefit for many neurodegenerative diseases, particularly myasthenia gravis and Alzheimer's disease.
format Journal
author Wasana Pratchayasakul
Anchalee Pongchaidecha
Nipon Chattipakorn
Siriporn Chattipakorn
author_facet Wasana Pratchayasakul
Anchalee Pongchaidecha
Nipon Chattipakorn
Siriporn Chattipakorn
author_sort Wasana Pratchayasakul
title Ethnobotany and ethnopharmacology of Tabernaemontana divaricata
title_short Ethnobotany and ethnopharmacology of Tabernaemontana divaricata
title_full Ethnobotany and ethnopharmacology of Tabernaemontana divaricata
title_fullStr Ethnobotany and ethnopharmacology of Tabernaemontana divaricata
title_full_unstemmed Ethnobotany and ethnopharmacology of Tabernaemontana divaricata
title_sort ethnobotany and ethnopharmacology of tabernaemontana divaricata
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=51349097371&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/60145
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