TP53 gene mutations of lung cancer patients in upper northern Thailand and environmental risk factors

• Main Authors: Kanokkan Bumroongkit, Bruce Rannala, Patrinee Traisathit, Metawee Srikummool, Yannawan Wongchai, Daoroong Kangwanpong
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=47549116173&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/60155
• Institution: Chiang Mai University

TP53 mutations are observed in about 40-70% of lung cancer tissues, and the hot spot codon mutations are in exons 5 through 8. Previous studies revealed that the distinct TP53 mutational pattern between population groups may be due to different racial or exogenous factors. This research aims to iden...