Preoperative irinotecan/5-FU/leucovorin plus concurrent radiotherapy in rectal cancer.

• Main Authors: Imjai Chitapanarux, Pimkhuan Kamnerdsupaphon, Vicharn Lorvidhaya, Paisit Siriwittayakorn, Ekkasit Tharavichitkul, Areewan Somwangprasert, Vimol Sukthomya
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=39749152414&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/60190
• Institution: Chiang Mai University

PURPOSE: To evaluate results of preoperative irinotecan/5-FU/leucovorin plus radiotherapy for locally-advanced rectal cancer. METHODS: Thirty-five patients with locally-advanced rectal cancer were treated with preoperative irradiation 46 Gy plus concurrent chemotherapy(irinotecan 10 mg/m(2)/d d1-d5,...