Differences in global gene expression in peripheral blood mononuclear cells indicate a significant role of the innate responses in progression of dengue fever but not dengue hemorrhagic fever

• Main Authors: Sukathida Ubol, Promsin Masrinoul, Jeerayut Chaijaruwanich, Siripen Kalayanarooj, Takol Charoensirisuthikul, Jitra Kasisith
• Format: Journal
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=44049104994&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/60473
• Institution: Chiang Mai University

Background. Dengue virus infection causes an array of symptoms ranging from dengue fever (DF) to dengue hemorrhagic fever (DHF). The pathophysiological processes behind these 2 clinical manifestations are unclear. Methods. In the present study, genomewide transcriptomes of peripheral blood mononucle...