Normative database of retinal nerve fiber layer and macular retinal thickness in a Thai population
Purpose: To investigate the distribution of retinal nerve fiber layer (RNFL) and macular retinal thickness measured by optical coherence tomography (OCT) in a Thai population. Methods: We studied one eye each of 250 healthy subjects [age ≥ 18 years; spherical refractive error within ±6 diopters (D);...
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th-cmuir.6653943832-605752018-09-10T03:45:36Z Normative database of retinal nerve fiber layer and macular retinal thickness in a Thai population Anita Manassakorn Winai Chaidaroon Somsanguan Ausayakhun Soontaree Aupapong Sopa Wattananikorn Medicine Purpose: To investigate the distribution of retinal nerve fiber layer (RNFL) and macular retinal thickness measured by optical coherence tomography (OCT) in a Thai population. Methods: We studied one eye each of 250 healthy subjects [age ≥ 18 years; spherical refractive error within ±6 diopters (D); astigmatism ≤3 D; no ocular pathology]. A complete eye examination, standard automated perimetry, and fast RNFL and macular thickness measurement by OCT were performed, and a disc photograph was taken. The distributions of both thicknesses, including their relationship with demographic data, were analyzed. Results: The mean ± SD age of the study population was 44.7 ± 12.2 years. The mean ± SD RNFL thickness was 109.3 ± 10.5 m, which was 10% thicker than that in the OCT normative database. RNFL decreased 2.3 m per decade (P < 0.001). Sex and spherical equivalent were not associated with RNFL thinning. The mean ± SD central foveal thickness was 183.2 ± 1.3 m. The macular thickness in the outer area was significantly thinner than that in the inner area (P < 0.001). The temporal regions were the thinnest among the four quadrants (P < 0.001). Thinning of all macular areas, except the center, was found to be associated with advancing age (P < 0.05). Conclusions: RNFL thickness in the measured Thai population was about 10% thicker than that in the original normative database. Macular thickness and RNFL thickness in the superior and inferior quadrants decreased with advancing age. © 2008 Japanese Ophthalmological Society (JOS). 2018-09-10T03:45:36Z 2018-09-10T03:45:36Z 2008-11-01 Journal 00215155 2-s2.0-57849132351 10.1007/s10384-008-0538-6 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=57849132351&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/60575 |
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Medicine Anita Manassakorn Winai Chaidaroon Somsanguan Ausayakhun Soontaree Aupapong Sopa Wattananikorn Normative database of retinal nerve fiber layer and macular retinal thickness in a Thai population |
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Purpose: To investigate the distribution of retinal nerve fiber layer (RNFL) and macular retinal thickness measured by optical coherence tomography (OCT) in a Thai population. Methods: We studied one eye each of 250 healthy subjects [age ≥ 18 years; spherical refractive error within ±6 diopters (D); astigmatism ≤3 D; no ocular pathology]. A complete eye examination, standard automated perimetry, and fast RNFL and macular thickness measurement by OCT were performed, and a disc photograph was taken. The distributions of both thicknesses, including their relationship with demographic data, were analyzed. Results: The mean ± SD age of the study population was 44.7 ± 12.2 years. The mean ± SD RNFL thickness was 109.3 ± 10.5 m, which was 10% thicker than that in the OCT normative database. RNFL decreased 2.3 m per decade (P < 0.001). Sex and spherical equivalent were not associated with RNFL thinning. The mean ± SD central foveal thickness was 183.2 ± 1.3 m. The macular thickness in the outer area was significantly thinner than that in the inner area (P < 0.001). The temporal regions were the thinnest among the four quadrants (P < 0.001). Thinning of all macular areas, except the center, was found to be associated with advancing age (P < 0.05). Conclusions: RNFL thickness in the measured Thai population was about 10% thicker than that in the original normative database. Macular thickness and RNFL thickness in the superior and inferior quadrants decreased with advancing age. © 2008 Japanese Ophthalmological Society (JOS). |
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Journal |
author |
Anita Manassakorn Winai Chaidaroon Somsanguan Ausayakhun Soontaree Aupapong Sopa Wattananikorn |
author_facet |
Anita Manassakorn Winai Chaidaroon Somsanguan Ausayakhun Soontaree Aupapong Sopa Wattananikorn |
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Anita Manassakorn |
title |
Normative database of retinal nerve fiber layer and macular retinal thickness in a Thai population |
title_short |
Normative database of retinal nerve fiber layer and macular retinal thickness in a Thai population |
title_full |
Normative database of retinal nerve fiber layer and macular retinal thickness in a Thai population |
title_fullStr |
Normative database of retinal nerve fiber layer and macular retinal thickness in a Thai population |
title_full_unstemmed |
Normative database of retinal nerve fiber layer and macular retinal thickness in a Thai population |
title_sort |
normative database of retinal nerve fiber layer and macular retinal thickness in a thai population |
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2018 |
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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=57849132351&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/60575 |
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