Ion beam intensity distribution in ion-bombarded areas of biological targets

• Main Authors: L. D. Yu, K. Prakrajang, T. Vilaithong, C. Tengsirivattana, S. Anuntalabhochai
• Format: Journal
• Published: 2018
• Subjects: Physics and Astronomy
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=58249124349&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/60721
• Institution: Chiang Mai University

The ion beam intensity distribution in an ion-beain-bombarded area is particularly important for treating biological targets that are location-sensitive to ion energy and fluence. In order to investigate the beam intensity distribution, we carried out a theoretical calculation. The theoretical study was started from an assumption of a certain 3-D distribution of the beam intensity for a fixed beam spot and was followed by integration to describe a scanning of this beam spot within a certain target area. The details of the calculations with an example of Gaussian distribution for the initial fixed beam spot are presented. The calculated result was compared with an experimentally-measured ion-beam intensity distribution, and good agreement was achieved. The scanning ion-beam intensity distribution was applied to guide ion-beam-induced gene transfer in biological cells such as the bacteria E. coli.