Novel sulfated octa- and decasaccharides from squid cartilage chondroitin sulfate E: Sequencing and application for determination of the epitope structure of the monoclonal antibody MO-225

A mixture of octa- and decasaccharides obtained by the digestion with the hyaluronidase of chondroitin sulfate E derived from squid cartilage was subfractionated into 20 and 23 different components, respectively, by anion-exchange HPLC. MALDI-TOF/MS was used to assign the sugar and sulfate compositi...

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Main Authors: Sarama Sathyaseelan Deepa, Kittiwan Kalayanamitra, Yumi Ito, Prachya Kongtawelert, Shigeyuki Fukui, Shuhei Yamada, Tadahisa Mikami, Kazuyuki Sugahara
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33847666790&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/60912
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Institution: Chiang Mai University