Curcumin as chemosensitizer

Curcumin as chemosensitizer

This overview presents curcumin as a significant chemosensitizer in cancer chemotherapy. Although the review focuses on curcumin and its analogues on multidrug resistance (MDR) reversal, the relevance of curcumin as a nuclear factor (NF)-κB blocker and sensitizer of many chemoresistant cancer cell l...

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Main Author: Pornngarm Limtrakul
Format: Book Series
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84934443974&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/60921
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Institution: Chiang Mai University
id th-cmuir.6653943832-60921
record_format dspace
spelling th-cmuir.6653943832-609212018-09-10T04:01:20Z Curcumin as chemosensitizer Pornngarm Limtrakul Biochemistry, Genetics and Molecular Biology This overview presents curcumin as a significant chemosensitizer in cancer chemotherapy. Although the review focuses on curcumin and its analogues on multidrug resistance (MDR) reversal, the relevance of curcumin as a nuclear factor (NF)-κB blocker and sensitizer of many chemoresistant cancer cell lines to chemotherapeutic agents will also be discussed. One of the major mechanisms of MDR is the enhanced ability of tumor cells to actively efflux drugs, leading to a decrease in cellular drug accumulation below toxic levels. © 2007 Springer. 2018-09-10T04:01:20Z 2018-09-10T04:01:20Z 2007-01-01 Book Series 00652598 2-s2.0-84934443974 10.1007/978-0-387-46401-5_12 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84934443974&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/60921
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Biochemistry, Genetics and Molecular Biology
spellingShingle Biochemistry, Genetics and Molecular Biology
Pornngarm Limtrakul
Curcumin as chemosensitizer
description This overview presents curcumin as a significant chemosensitizer in cancer chemotherapy. Although the review focuses on curcumin and its analogues on multidrug resistance (MDR) reversal, the relevance of curcumin as a nuclear factor (NF)-κB blocker and sensitizer of many chemoresistant cancer cell lines to chemotherapeutic agents will also be discussed. One of the major mechanisms of MDR is the enhanced ability of tumor cells to actively efflux drugs, leading to a decrease in cellular drug accumulation below toxic levels. © 2007 Springer.
format Book Series
author Pornngarm Limtrakul
author_facet Pornngarm Limtrakul
author_sort Pornngarm Limtrakul
title Curcumin as chemosensitizer
title_short Curcumin as chemosensitizer
title_full Curcumin as chemosensitizer
title_fullStr Curcumin as chemosensitizer
title_full_unstemmed Curcumin as chemosensitizer
title_sort curcumin as chemosensitizer
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84934443974&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/60921
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