Evidence of intragenic recombination in G1 rotavirus VP7 genes

The G1 rotavirus is the most widespread genotype causing acute gastroenteritis in children. In an attempt to investigate the occurrence of intragenic recombination, 131 complete coding region sequences of VP7 genes of the G1 rotaviruses in GenBank were examined. Three hitherto-unreported intragenic...

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Bibliographic Details
Main Authors: Gia Phan Tung, Shoko Okitsu, Niwat Maneekarn, Hiroshi Ushijima
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=35348840909&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/61128
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Institution: Chiang Mai University
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Summary:The G1 rotavirus is the most widespread genotype causing acute gastroenteritis in children. In an attempt to investigate the occurrence of intragenic recombination, 131 complete coding region sequences of VP7 genes of the G1 rotaviruses in GenBank were examined. Three hitherto-unreported intragenic recombinant rotaviruses were identified. It was noteworthy that two different types (interlineage and intersublineage) of intragenic recombination in rotaviruses were also found. This is the first report to demonstrate the existence of intragenic recombinations between interlineage and intersublineage in G1 rotaviruses. Copyright © 2007, American Society for Microbiology. All Rights Reserved.