Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand

Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand

We report the long-term efficacy of highly active antiretroviral therapy (HAART) in 107 antiretroviral-naive human immunodeficiency virus (HIV)-infected Thai children. In an intention-to-treat analysis, 70% of the children had undetectable HIV RNA titers after 192 weeks of HAART. The mean CD4 cell p...

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Main Authors: Thanyawee Puthanakit, Linda Aurpibul, Peninnah Oberdorfer, Noppadon Akarathum, Suparat Kanjanavanit, Pornphun Wannarit, Thira Sirisanthana, Virat Sirisanthana
Format: Journal
Published: 2018
Subjects:
Medicine
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=34848919230&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/61256
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-612562018-09-10T04:07:34Z Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand Thanyawee Puthanakit Linda Aurpibul Peninnah Oberdorfer Noppadon Akarathum Suparat Kanjanavanit Pornphun Wannarit Thira Sirisanthana Virat Sirisanthana Medicine We report the long-term efficacy of highly active antiretroviral therapy (HAART) in 107 antiretroviral-naive human immunodeficiency virus (HIV)-infected Thai children. In an intention-to-treat analysis, 70% of the children had undetectable HIV RNA titers after 192 weeks of HAART. The mean CD4 cell percentage increased from 5.3% to 26.6%. HAART is effective for HIV-infected children in this resource-poor setting despite initiation of treatment in the advanced stage of disease. © 2007 Lippincott Williams & Wilkins, Inc. 2018-09-10T04:07:34Z 2018-09-10T04:07:34Z 2007-10-01 Journal 08913668 2-s2.0-34848919230 10.1097/INF.0b013e318125720a https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=34848919230&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/61256
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Thanyawee Puthanakit
Linda Aurpibul
Peninnah Oberdorfer
Noppadon Akarathum
Suparat Kanjanavanit
Pornphun Wannarit
Thira Sirisanthana
Virat Sirisanthana
Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand
description We report the long-term efficacy of highly active antiretroviral therapy (HAART) in 107 antiretroviral-naive human immunodeficiency virus (HIV)-infected Thai children. In an intention-to-treat analysis, 70% of the children had undetectable HIV RNA titers after 192 weeks of HAART. The mean CD4 cell percentage increased from 5.3% to 26.6%. HAART is effective for HIV-infected children in this resource-poor setting despite initiation of treatment in the advanced stage of disease. © 2007 Lippincott Williams & Wilkins, Inc.
format Journal
author Thanyawee Puthanakit
Linda Aurpibul
Peninnah Oberdorfer
Noppadon Akarathum
Suparat Kanjanavanit
Pornphun Wannarit
Thira Sirisanthana
Virat Sirisanthana
author_facet Thanyawee Puthanakit
Linda Aurpibul
Peninnah Oberdorfer
Noppadon Akarathum
Suparat Kanjanavanit
Pornphun Wannarit
Thira Sirisanthana
Virat Sirisanthana
author_sort Thanyawee Puthanakit
title Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand
title_short Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand
title_full Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand
title_fullStr Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand
title_full_unstemmed Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand
title_sort sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in thailand
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=34848919230&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/61256
_version_ 1681425586809995264

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