Effect of doses on the bioavailability of phenytoin from a prompt-release and an extended-release preparation: Single dose study

• Main Authors: Noppamas Rojanasthien, Nuchanart Chaichana, Supanimit Teekachunhatean, Boonyium Kumsorn, Chaichan Sangdee, Siwaporn Chankrachang
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=35848931680&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/61265
• Institution: Chiang Mai University

Objective: To determine the effect of doses on the bioavailability of a prompt-release and an extended-release phenytoin capsule after given as single doses. Material and Method: Eight healthy male volunteers were given single oral doses of 100, 200, and 300 mg of a prompt-release preparation (Ditoi...