Curcumin contributes to in vitro removal of non-transferrin bound iron by deferiprone and desferrioxamine in thalassemic plasma

• Main Authors: S. Srichairatanakool, C. Thephinlap, C. Phisalaphong, J. B. Porter, S. Fucharoen
• Format: Journal
• Published: 2018
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=34648819489&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/61371
• Institution: Chiang Mai University

Non-transferrin-bound iron (NTBI) is detectable in plasma of β-thalassemia patients with transfusional iron overload. This form of iron may cause oxidative tissue damage and increased iron uptake, into several vital organs. Removal of NTBI species is incomplete and transient using standard intermitt...