Biotransformation of cortexolone to hydrocortisone by molds using a rapid color-development assay

• المؤلفون الرئيسيون: J. Manosroi, Y. Chisti, A. Manosroi
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33748317926&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/61508

The capacity of 22 molds for 11β-hydroxylation of cortexolone (Reichstein's compound S) to hydrocortisone were assessed. The biotransformation capacity was compared for solid-state and submerged monocultures of molds that were otherwise under identical conditions. Thin-layer chromatography and...