Anti-proliferative activity of essential oil extracted from Thai medicinal plants on KB and P388 cell lines

Anti-proliferative activity of essential oil extracted from Thai medicinal plants on KB and P388 cell lines

Anti-proliferative activity of essential oil from 17 Thai medicinal plants on human mouth epidermal carcinoma (KB) and murine leukemia (P388) cell lines using MTT assay were investigated. An amount of 1×104cells/well of KB cell line and 1×105cells/well of P388 cell line were treated with the oil sam...

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Main Authors: Jiradej Manosroi, Pongsathorn Dhumtanom, Aranya Manosroi
Format: Journal
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Medicine
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33645866178&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/61529
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-615292018-09-11T09:00:35Z Anti-proliferative activity of essential oil extracted from Thai medicinal plants on KB and P388 cell lines Jiradej Manosroi Pongsathorn Dhumtanom Aranya Manosroi Biochemistry, Genetics and Molecular Biology Medicine Anti-proliferative activity of essential oil from 17 Thai medicinal plants on human mouth epidermal carcinoma (KB) and murine leukemia (P388) cell lines using MTT assay were investigated. An amount of 1×104cells/well of KB cell line and 1×105cells/well of P388 cell line were treated with the oil samples at different concentrations ranging from 0.019 to 4.962 mg/ml. In KB cell line, Guava (Psidium guajava L.) leaf oil showed the highest anti-proliferative activity with the IC50value of 0.0379 mg/ml (4.37 times more potent than vincristine) whereas Sweet Basil (Ocimum basilicum L.) oil gave the highest anti-proliferative activity with the IC50value of 0.0362 mg/ml (12.7 times less potent than 5-FU) in P388 cell line. The results demonstrated the potential of essential oil from Thai medicinal plants for cancer treatment. © 2005 Elsevier Ireland Ltd. All rights reserved. 2018-09-11T08:54:39Z 2018-09-11T08:54:39Z 2006-04-08 Journal 03043835 2-s2.0-33645866178 10.1016/j.canlet.2005.04.021 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33645866178&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/61529
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Biochemistry, Genetics and Molecular Biology
Medicine
spellingShingle Biochemistry, Genetics and Molecular Biology
Medicine
Jiradej Manosroi
Pongsathorn Dhumtanom
Aranya Manosroi
Anti-proliferative activity of essential oil extracted from Thai medicinal plants on KB and P388 cell lines
description Anti-proliferative activity of essential oil from 17 Thai medicinal plants on human mouth epidermal carcinoma (KB) and murine leukemia (P388) cell lines using MTT assay were investigated. An amount of 1×104cells/well of KB cell line and 1×105cells/well of P388 cell line were treated with the oil samples at different concentrations ranging from 0.019 to 4.962 mg/ml. In KB cell line, Guava (Psidium guajava L.) leaf oil showed the highest anti-proliferative activity with the IC50value of 0.0379 mg/ml (4.37 times more potent than vincristine) whereas Sweet Basil (Ocimum basilicum L.) oil gave the highest anti-proliferative activity with the IC50value of 0.0362 mg/ml (12.7 times less potent than 5-FU) in P388 cell line. The results demonstrated the potential of essential oil from Thai medicinal plants for cancer treatment. © 2005 Elsevier Ireland Ltd. All rights reserved.
format Journal
author Jiradej Manosroi
Pongsathorn Dhumtanom
Aranya Manosroi
author_facet Jiradej Manosroi
Pongsathorn Dhumtanom
Aranya Manosroi
author_sort Jiradej Manosroi
title Anti-proliferative activity of essential oil extracted from Thai medicinal plants on KB and P388 cell lines
title_short Anti-proliferative activity of essential oil extracted from Thai medicinal plants on KB and P388 cell lines
title_full Anti-proliferative activity of essential oil extracted from Thai medicinal plants on KB and P388 cell lines
title_fullStr Anti-proliferative activity of essential oil extracted from Thai medicinal plants on KB and P388 cell lines
title_full_unstemmed Anti-proliferative activity of essential oil extracted from Thai medicinal plants on KB and P388 cell lines
title_sort anti-proliferative activity of essential oil extracted from thai medicinal plants on kb and p388 cell lines
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33645866178&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/61529
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