Synthesis and in vitro activities of ferrocenic aminohydroxynaphthoquinones against Toxoplasma gondii and Plasmodium falciparum

• المؤلفون الرئيسيون: Apiwat Baramee, Alexandra Coppin, Marlène Mortuaire, Lydie Pelinski, Stanislas Tomavo, Jacques Brocard
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=31044441086&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/61537
• المؤسسة: Chiang Mai University

Fourteen ferrocenyl aminohydroxynaphthoquinones, analogues of atovaquone, were synthesized from the hydroxynaphthoquinone core. These novel atovaquone derivatives were tested for their in vitro activity against two apicomplexan parasites of medical importance, Toxoplasma gondii and Plasmodium falcip...