Expression of cyclooxygenase-2 in colorectal adenocarcinoma is associated with p53 accumulation and hdm2 overexpression

• Main Authors: Ratchada Cressey, Sarunya Pimpa, Waragorn Tontrong, Onusa Watananupong, Nirush Leartprasertsuke
• 格式: 雜誌
• 出版: 2018
• 主題: Biochemistry, Genetics and Molecular Biology; Medicine
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33644657093&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/61538

Elevated cyclooxygenase-2 (COX-2) expression has been observed in various types of cancer. Induction of COX-2 expression has been reported to increase invasiveness and angiogenesis of tumours. While COX-2 overexpression has been repeatedly proven to promote tumor growth, little is known about what i...