High-grade squamous intraepithelial lesion with endocervical cone margin involvement after cervical loop electrosurgical excision: What should a clinician do?

This study was undertaken to evaluate the incidence and severity of residual lesions in women featuring highgrade squamous intraepithelial lesion (HSIL) histology with endocervical cone margin involvement after the loop electrosurgical excision procedure (LEEP). The medical records of women undergoi...

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Main Authors: Sitthicha Siriaree, Jatupol Srisomboon, Chumnan Kietpeerakool, Surapan Khunamornpong, Sumalee Siriaunkgul, Apaporn Natpratan, Sumon Pratheapjarus, Amornrat Futemwong, Uraporn Chantarasenawong
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/61544
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-615442018-09-11T09:01:11Z High-grade squamous intraepithelial lesion with endocervical cone margin involvement after cervical loop electrosurgical excision: What should a clinician do? Sitthicha Siriaree Jatupol Srisomboon Chumnan Kietpeerakool Surapan Khunamornpong Sumalee Siriaunkgul Apaporn Natpratan Sumon Pratheapjarus Amornrat Futemwong Uraporn Chantarasenawong Biochemistry, Genetics and Molecular Biology Medicine This study was undertaken to evaluate the incidence and severity of residual lesions in women featuring highgrade squamous intraepithelial lesion (HSIL) histology with endocervical cone margin involvement after the loop electrosurgical excision procedure (LEEP). The medical records of women undergoing LEEP at Chiang Mai University Hospital between October 2004 and February 2006 were retrospectively reviewed and 74 cases were identified. Nineteen women were excluded because of loss to follow-up. The remaining 4 were referred to other hospitals and 2 declined re-excision, leaving a study population of 55 women for analysis. Mean age ± SD of the patients was 48.5 ± 8.9 years. Residual lesions were noted in 26 (47.3%, 95%CI= 33.7 to 61.2). Four (7.3%) had unrecognized invasive cervical carcinoma in subsequent specimens. In conclusion, approximately half of women with positive endocervical cone margins after LEEP for HSIL histology have residual disease. Repeat diagnostic excision is recommended for evaluation of lesions and severity. 2018-09-11T08:54:47Z 2018-09-11T08:54:47Z 2006-01-01 Journal 2476762X 15137368 2-s2.0-39049192098 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=39049192098&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/61544
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Biochemistry, Genetics and Molecular Biology
Medicine
spellingShingle Biochemistry, Genetics and Molecular Biology
Medicine
Sitthicha Siriaree
Jatupol Srisomboon
Chumnan Kietpeerakool
Surapan Khunamornpong
Sumalee Siriaunkgul
Apaporn Natpratan
Sumon Pratheapjarus
Amornrat Futemwong
Uraporn Chantarasenawong
High-grade squamous intraepithelial lesion with endocervical cone margin involvement after cervical loop electrosurgical excision: What should a clinician do?
description This study was undertaken to evaluate the incidence and severity of residual lesions in women featuring highgrade squamous intraepithelial lesion (HSIL) histology with endocervical cone margin involvement after the loop electrosurgical excision procedure (LEEP). The medical records of women undergoing LEEP at Chiang Mai University Hospital between October 2004 and February 2006 were retrospectively reviewed and 74 cases were identified. Nineteen women were excluded because of loss to follow-up. The remaining 4 were referred to other hospitals and 2 declined re-excision, leaving a study population of 55 women for analysis. Mean age ± SD of the patients was 48.5 ± 8.9 years. Residual lesions were noted in 26 (47.3%, 95%CI= 33.7 to 61.2). Four (7.3%) had unrecognized invasive cervical carcinoma in subsequent specimens. In conclusion, approximately half of women with positive endocervical cone margins after LEEP for HSIL histology have residual disease. Repeat diagnostic excision is recommended for evaluation of lesions and severity.
format Journal
author Sitthicha Siriaree
Jatupol Srisomboon
Chumnan Kietpeerakool
Surapan Khunamornpong
Sumalee Siriaunkgul
Apaporn Natpratan
Sumon Pratheapjarus
Amornrat Futemwong
Uraporn Chantarasenawong
author_facet Sitthicha Siriaree
Jatupol Srisomboon
Chumnan Kietpeerakool
Surapan Khunamornpong
Sumalee Siriaunkgul
Apaporn Natpratan
Sumon Pratheapjarus
Amornrat Futemwong
Uraporn Chantarasenawong
author_sort Sitthicha Siriaree
title High-grade squamous intraepithelial lesion with endocervical cone margin involvement after cervical loop electrosurgical excision: What should a clinician do?
title_short High-grade squamous intraepithelial lesion with endocervical cone margin involvement after cervical loop electrosurgical excision: What should a clinician do?
title_full High-grade squamous intraepithelial lesion with endocervical cone margin involvement after cervical loop electrosurgical excision: What should a clinician do?
title_fullStr High-grade squamous intraepithelial lesion with endocervical cone margin involvement after cervical loop electrosurgical excision: What should a clinician do?
title_full_unstemmed High-grade squamous intraepithelial lesion with endocervical cone margin involvement after cervical loop electrosurgical excision: What should a clinician do?
title_sort high-grade squamous intraepithelial lesion with endocervical cone margin involvement after cervical loop electrosurgical excision: what should a clinician do?
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=39049192098&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/61544
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