Northern thai women with high grade squamous intraepithelial lesion on cervical cytology have high prevalence of underlying invasive Carcinoma

The aim of this study was to determine the underlying pathology of women with high grade squamous intraepithelial lesion (HSIL) on cervical cytology. A total of 681 women with HSIL cytology undergoing colposcopic examination at Chiang Mai University Hospital (CMUH) between January 2000 and December...

Full description

Saved in:
Bibliographic Details
Main Authors: Nuttavut Kantathavorn, Chailert Phongnarisorn, Jatupol Srisomboon, Prapaporn Suprasert, Sumalee Siriaunkgul, Surapan Khunamornpong, Kanchana Nimmanahaeminda
Format: Journal
Published: 2018
Subjects:
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=39049184853&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/61545
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Chiang Mai University
id th-cmuir.6653943832-61545
record_format dspace
spelling th-cmuir.6653943832-615452018-09-11T09:01:11Z Northern thai women with high grade squamous intraepithelial lesion on cervical cytology have high prevalence of underlying invasive Carcinoma Nuttavut Kantathavorn Chailert Phongnarisorn Jatupol Srisomboon Prapaporn Suprasert Sumalee Siriaunkgul Surapan Khunamornpong Kanchana Nimmanahaeminda Biochemistry, Genetics and Molecular Biology Medicine The aim of this study was to determine the underlying pathology of women with high grade squamous intraepithelial lesion (HSIL) on cervical cytology. A total of 681 women with HSIL cytology undergoing colposcopic examination at Chiang Mai University Hospital (CMUH) between January 2000 and December 2005 were evaluated for the underlying cervical pathology. The final pathology was diagnosed from the most severe lesions obtained by punch biopsy, loop electrosurgical procedure, cold knife conization or hysterectomy. Underlying high grade cervical lesions including cervical intraepithelial neoplasia grade 2, 3 and adenocarcinoma in situ were noted in 502 (73.7%) women. Invasive cervical carcinoma was identified in 141 (20.7%). The remaining 38 (5.6%) had either low grade or no intraepithelial lesions. No significant difference in the prevalence of underlying high grade and invasive lesions was noted between women with cytologic diagnosis of HSIL from CMUH and other hospitals. In conclusion, northern Thai women with HSIL cytology are at significant risk of having underlying severe cervical lesions, and especially invasive carcinoma which is detected in approximately one-fifth of the cases. 2018-09-11T08:54:47Z 2018-09-11T08:54:47Z 2006-01-01 Journal 2476762X 15137368 2-s2.0-39049184853 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=39049184853&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/61545
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Biochemistry, Genetics and Molecular Biology
Medicine
spellingShingle Biochemistry, Genetics and Molecular Biology
Medicine
Nuttavut Kantathavorn
Chailert Phongnarisorn
Jatupol Srisomboon
Prapaporn Suprasert
Sumalee Siriaunkgul
Surapan Khunamornpong
Kanchana Nimmanahaeminda
Northern thai women with high grade squamous intraepithelial lesion on cervical cytology have high prevalence of underlying invasive Carcinoma
description The aim of this study was to determine the underlying pathology of women with high grade squamous intraepithelial lesion (HSIL) on cervical cytology. A total of 681 women with HSIL cytology undergoing colposcopic examination at Chiang Mai University Hospital (CMUH) between January 2000 and December 2005 were evaluated for the underlying cervical pathology. The final pathology was diagnosed from the most severe lesions obtained by punch biopsy, loop electrosurgical procedure, cold knife conization or hysterectomy. Underlying high grade cervical lesions including cervical intraepithelial neoplasia grade 2, 3 and adenocarcinoma in situ were noted in 502 (73.7%) women. Invasive cervical carcinoma was identified in 141 (20.7%). The remaining 38 (5.6%) had either low grade or no intraepithelial lesions. No significant difference in the prevalence of underlying high grade and invasive lesions was noted between women with cytologic diagnosis of HSIL from CMUH and other hospitals. In conclusion, northern Thai women with HSIL cytology are at significant risk of having underlying severe cervical lesions, and especially invasive carcinoma which is detected in approximately one-fifth of the cases.
format Journal
author Nuttavut Kantathavorn
Chailert Phongnarisorn
Jatupol Srisomboon
Prapaporn Suprasert
Sumalee Siriaunkgul
Surapan Khunamornpong
Kanchana Nimmanahaeminda
author_facet Nuttavut Kantathavorn
Chailert Phongnarisorn
Jatupol Srisomboon
Prapaporn Suprasert
Sumalee Siriaunkgul
Surapan Khunamornpong
Kanchana Nimmanahaeminda
author_sort Nuttavut Kantathavorn
title Northern thai women with high grade squamous intraepithelial lesion on cervical cytology have high prevalence of underlying invasive Carcinoma
title_short Northern thai women with high grade squamous intraepithelial lesion on cervical cytology have high prevalence of underlying invasive Carcinoma
title_full Northern thai women with high grade squamous intraepithelial lesion on cervical cytology have high prevalence of underlying invasive Carcinoma
title_fullStr Northern thai women with high grade squamous intraepithelial lesion on cervical cytology have high prevalence of underlying invasive Carcinoma
title_full_unstemmed Northern thai women with high grade squamous intraepithelial lesion on cervical cytology have high prevalence of underlying invasive Carcinoma
title_sort northern thai women with high grade squamous intraepithelial lesion on cervical cytology have high prevalence of underlying invasive carcinoma
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=39049184853&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/61545
_version_ 1681425640748744704