Enzymatic processes for fine chemicals and pharmaceuticals: Kinetic simulation for optimal R-phenylacetylcarbinol production

• Main Authors: N. Leksawasdi, B. Rosche, P. Rogers
• Format: Book Series
• Published: 2018
• Subjects: Chemical Engineering; Chemistry; Materials Science; Physics and Astronomy
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33745783275&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/61565
• Institution: Chiang Mai University

An optimal feeding strategy with a 1:1.2 molar ratio of benzaldehyde: pyruvate has been developed to maximize the enzymatic production of the pharmaceutical intermediate R-phenylacetylcarbinol (PAC) based on a previously published model for this intermediate. The results of the simulation indicate w...