Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study

Objective: To investigate the risk of hepatitis C virus (HCV) infection in healthy blood donors in Thailand Material and Method: We performed a case-control study of 435 HCV-seropositive blood donors and 894 HCV-seronegative blood donors as controls. The study was done with direct interview regardin...

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Main Authors: Tawesak Tanwandee, Teerha Piratvisuth, Kannilka Phornphutkul, Pisaln Mairiang, Parichart Permpikul, Yong Poovorawan
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/61809
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-618092018-09-11T08:59:32Z Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study Tawesak Tanwandee Teerha Piratvisuth Kannilka Phornphutkul Pisaln Mairiang Parichart Permpikul Yong Poovorawan Medicine Objective: To investigate the risk of hepatitis C virus (HCV) infection in healthy blood donors in Thailand Material and Method: We performed a case-control study of 435 HCV-seropositive blood donors and 894 HCV-seronegative blood donors as controls. The study was done with direct interview regarding demographic characteristics and risk factors. Odds ratios (OR) with 95% confidence intervals (Cls) were calculated by using conditional logistic regression. Results: The final multivariable model included only the following independent HCV risk factors: intravenous drug user (IDU) (OR = 61.5; 95%CI, 26.6-142.5), previous blood or blood products transfusion (OR = 12.3; 95%CI, 7.6 -19.9), sharing of razors (OR = 2.3, 95%CI, 1.6-3.2),unsafe injection (OR = 3.3, 95%CI, 1.8-5.9), unused condom (OR = 1.6; 95%CI, 1.1, 2.4). No risk was shown for a history of tattoo, ear piercing, or acupuncture and multiple sexual partners. Conclusion: The risk factors for HCV infection in healthy blood donors in Thailand are IDU, past history of blood transfusion and unsafe injection. 2018-09-11T08:59:32Z 2018-09-11T08:59:32Z 2006-11-01 Journal 01252208 01252208 2-s2.0-33846694227 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33846694227&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/61809
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Tawesak Tanwandee
Teerha Piratvisuth
Kannilka Phornphutkul
Pisaln Mairiang
Parichart Permpikul
Yong Poovorawan
Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study
description Objective: To investigate the risk of hepatitis C virus (HCV) infection in healthy blood donors in Thailand Material and Method: We performed a case-control study of 435 HCV-seropositive blood donors and 894 HCV-seronegative blood donors as controls. The study was done with direct interview regarding demographic characteristics and risk factors. Odds ratios (OR) with 95% confidence intervals (Cls) were calculated by using conditional logistic regression. Results: The final multivariable model included only the following independent HCV risk factors: intravenous drug user (IDU) (OR = 61.5; 95%CI, 26.6-142.5), previous blood or blood products transfusion (OR = 12.3; 95%CI, 7.6 -19.9), sharing of razors (OR = 2.3, 95%CI, 1.6-3.2),unsafe injection (OR = 3.3, 95%CI, 1.8-5.9), unused condom (OR = 1.6; 95%CI, 1.1, 2.4). No risk was shown for a history of tattoo, ear piercing, or acupuncture and multiple sexual partners. Conclusion: The risk factors for HCV infection in healthy blood donors in Thailand are IDU, past history of blood transfusion and unsafe injection.
format Journal
author Tawesak Tanwandee
Teerha Piratvisuth
Kannilka Phornphutkul
Pisaln Mairiang
Parichart Permpikul
Yong Poovorawan
author_facet Tawesak Tanwandee
Teerha Piratvisuth
Kannilka Phornphutkul
Pisaln Mairiang
Parichart Permpikul
Yong Poovorawan
author_sort Tawesak Tanwandee
title Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study
title_short Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study
title_full Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study
title_fullStr Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study
title_full_unstemmed Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study
title_sort risk factors of hepatitis c virus infection in blood donors in thailand: a multicenter case-control study
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33846694227&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/61809
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