Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study
Objective: To investigate the risk of hepatitis C virus (HCV) infection in healthy blood donors in Thailand Material and Method: We performed a case-control study of 435 HCV-seropositive blood donors and 894 HCV-seronegative blood donors as controls. The study was done with direct interview regardin...
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th-cmuir.6653943832-618092018-09-11T08:59:32Z Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study Tawesak Tanwandee Teerha Piratvisuth Kannilka Phornphutkul Pisaln Mairiang Parichart Permpikul Yong Poovorawan Medicine Objective: To investigate the risk of hepatitis C virus (HCV) infection in healthy blood donors in Thailand Material and Method: We performed a case-control study of 435 HCV-seropositive blood donors and 894 HCV-seronegative blood donors as controls. The study was done with direct interview regarding demographic characteristics and risk factors. Odds ratios (OR) with 95% confidence intervals (Cls) were calculated by using conditional logistic regression. Results: The final multivariable model included only the following independent HCV risk factors: intravenous drug user (IDU) (OR = 61.5; 95%CI, 26.6-142.5), previous blood or blood products transfusion (OR = 12.3; 95%CI, 7.6 -19.9), sharing of razors (OR = 2.3, 95%CI, 1.6-3.2),unsafe injection (OR = 3.3, 95%CI, 1.8-5.9), unused condom (OR = 1.6; 95%CI, 1.1, 2.4). No risk was shown for a history of tattoo, ear piercing, or acupuncture and multiple sexual partners. Conclusion: The risk factors for HCV infection in healthy blood donors in Thailand are IDU, past history of blood transfusion and unsafe injection. 2018-09-11T08:59:32Z 2018-09-11T08:59:32Z 2006-11-01 Journal 01252208 01252208 2-s2.0-33846694227 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33846694227&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/61809 |
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Medicine Tawesak Tanwandee Teerha Piratvisuth Kannilka Phornphutkul Pisaln Mairiang Parichart Permpikul Yong Poovorawan Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study |
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Objective: To investigate the risk of hepatitis C virus (HCV) infection in healthy blood donors in Thailand Material and Method: We performed a case-control study of 435 HCV-seropositive blood donors and 894 HCV-seronegative blood donors as controls. The study was done with direct interview regarding demographic characteristics and risk factors. Odds ratios (OR) with 95% confidence intervals (Cls) were calculated by using conditional logistic regression. Results: The final multivariable model included only the following independent HCV risk factors: intravenous drug user (IDU) (OR = 61.5; 95%CI, 26.6-142.5), previous blood or blood products transfusion (OR = 12.3; 95%CI, 7.6 -19.9), sharing of razors (OR = 2.3, 95%CI, 1.6-3.2),unsafe injection (OR = 3.3, 95%CI, 1.8-5.9), unused condom (OR = 1.6; 95%CI, 1.1, 2.4). No risk was shown for a history of tattoo, ear piercing, or acupuncture and multiple sexual partners. Conclusion: The risk factors for HCV infection in healthy blood donors in Thailand are IDU, past history of blood transfusion and unsafe injection. |
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Tawesak Tanwandee Teerha Piratvisuth Kannilka Phornphutkul Pisaln Mairiang Parichart Permpikul Yong Poovorawan |
author_facet |
Tawesak Tanwandee Teerha Piratvisuth Kannilka Phornphutkul Pisaln Mairiang Parichart Permpikul Yong Poovorawan |
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Tawesak Tanwandee |
title |
Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study |
title_short |
Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study |
title_full |
Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study |
title_fullStr |
Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study |
title_full_unstemmed |
Risk factors of hepatitis C virus infection in blood donors in Thailand: A multicenter case-control study |
title_sort |
risk factors of hepatitis c virus infection in blood donors in thailand: a multicenter case-control study |
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2018 |
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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33846694227&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/61809 |
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