Estimating glomerular filtration rate in asian patients with chronic kidney diseases from bioelectrical impedance analysis
Background: Estimation of glomerular filtration rate (GFR) is usually determined from 24-hour urine collection, but it is time-consuming, and difficult in clinical practice. The authors attempted to select an accurate and safe, but more convenient test to obtain an estimated GFR. Objective: To compa...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Journal |
| Published: |
2018
|
| Subjects: | |
| Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33750970890&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/61820 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Chiang Mai University |
| Summary: | Background: Estimation of glomerular filtration rate (GFR) is usually determined from 24-hour urine collection, but it is time-consuming, and difficult in clinical practice. The authors attempted to select an accurate and safe, but more convenient test to obtain an estimated GFR. Objective: To compare estimation of GFR by Bioelectrical impedance analysis (BIA) with GFR calculated by 24-hour urine averaged creatinine clearance and urea clearance (Ccr-Cu-GFR). Material and Method: The authors examined 79 non-diabetic chronic kidney disease (CKD) patients that had estimated GFR between 15 and 89 ml/min/1.73 m 2. Subjects were categorized into three subgroups according to K/DOQI-CKD classification: GFR of 60-89 ml/min/1.73m 2 (stage 2, 5 subjects), 30-59 ml/min/ 1.73m 2 (stage 3, 31 subjects), and 15-29 ml/min/1.73m 2 (stage 4, 43 subjects). Results: The mean value of Ccr-Cu-GFR was 33.79 ± 14.78 ml/min/1.73 m 2 and GFR by BIA (BIA-GFR), 34.63 ± 14.86 ml/min/1.73 m 2 with no overall statistical differences (p = 0.838). In stage 3 CKD patients, the mean BIA-GFR and Ccr-Cu-GFR were similar (38.84 ± 12.47 vs 41.16 ± 9.17, p = 0.399) while in stage 2 CKD, BIAGFR tended to underestimate (63.50 ± 19.35 vs 70.94 ± 7.82, p = 0.407) and in stage 4 CKD, BIA-GFR significantly overestimated Ccr-Cu-GFR (27.31 ± 9.11 vs 23.76 ± 5.68, p = 0.040). Conclusion: The findings suggest that BIA-GFR in non-diabetic CKD patients closely resembled with Ccr-Cu-GFR especially in stage 3 CKD patients. BIA-GFR may be considered as a more convenient test for an assessment of GFR in non-diabetic CKD patients. |
|---|