Outcomes of loop electrosurgical excision procedure for cervical neoplasia in human immunodeficiency virus-infected women

The objective of this study was to evaluate the treatment outcomes and complications in human immunodeficiency virus (HIV)-infected women undergoing loop electrosurgical excision procedure (LEEP) for cervical neoplasia. The medical record of 60 evaluable HIV-infected women who had abnormal Papanicol...

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Main Authors: C. Kietpeerakool, J. Srisomboon, P. Suprasert, C. Phongnarisorn, K. Charoenkwan, C. Cheewakriangkrai, S. Siriaree, C. Tantipalakorn, A. Pantusart
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Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/61868
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-618682018-09-11T09:00:29Z Outcomes of loop electrosurgical excision procedure for cervical neoplasia in human immunodeficiency virus-infected women C. Kietpeerakool J. Srisomboon P. Suprasert C. Phongnarisorn K. Charoenkwan C. Cheewakriangkrai S. Siriaree C. Tantipalakorn A. Pantusart Medicine The objective of this study was to evaluate the treatment outcomes and complications in human immunodeficiency virus (HIV)-infected women undergoing loop electrosurgical excision procedure (LEEP) for cervical neoplasia. The medical record of 60 evaluable HIV-infected women who had abnormal Papanicolaou (Pap) smear and underwent LEEP following colposcopy at Chiang Mai University Hospital between May 1998 and June 2004 was reviewed. Thirty-one (51.7%) had associated genital infection at screening. Twenty-five (41.7%) had opportunistic infection, but only 18 (30.0%) were treated with antiretroviral therapy. The most common abnormal Pap smear was high-grade squamous intraepithelial lesion (46.7%), followed by low-grade squamous intraepithelial lesion (40.0%). Forty (66.7%) women had clear surgical margins after LEEP. Only one (1.7%) woman had severe intraoperative hemorrhage. Early and late postoperative hemorrhage were noted in three (5%) women of each period. Localized infection of the cervix was detected in seven (11.7%) women. Two (3.3%) women developed cervical stenosis at 6 months after LEEP. There was no significant difference in overall complications between HIV-infected women and the control group (P = 0.24). Among 60 HIV-infected women, no statistical difference in the rate of margins involvement (P = 1.00) and complications (P = 0.85) could be demonstrated between HIV-infected women who received antiretroviral therapy and those who did not. Disease-free rate at 6 and 12 months were 97.1% and 88%, respectively. These data demonstrated that LEEP appears to be safe and effective in HIV-infected women. © 2006, Copyright the Authors. 2018-09-11T09:00:29Z 2018-09-11T09:00:29Z 2006-05-01 Journal 15251438 1048891X 2-s2.0-33745086207 10.1111/j.1525-1438.2006.00518.x https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33745086207&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/61868
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
C. Kietpeerakool
J. Srisomboon
P. Suprasert
C. Phongnarisorn
K. Charoenkwan
C. Cheewakriangkrai
S. Siriaree
C. Tantipalakorn
A. Pantusart
Outcomes of loop electrosurgical excision procedure for cervical neoplasia in human immunodeficiency virus-infected women
description The objective of this study was to evaluate the treatment outcomes and complications in human immunodeficiency virus (HIV)-infected women undergoing loop electrosurgical excision procedure (LEEP) for cervical neoplasia. The medical record of 60 evaluable HIV-infected women who had abnormal Papanicolaou (Pap) smear and underwent LEEP following colposcopy at Chiang Mai University Hospital between May 1998 and June 2004 was reviewed. Thirty-one (51.7%) had associated genital infection at screening. Twenty-five (41.7%) had opportunistic infection, but only 18 (30.0%) were treated with antiretroviral therapy. The most common abnormal Pap smear was high-grade squamous intraepithelial lesion (46.7%), followed by low-grade squamous intraepithelial lesion (40.0%). Forty (66.7%) women had clear surgical margins after LEEP. Only one (1.7%) woman had severe intraoperative hemorrhage. Early and late postoperative hemorrhage were noted in three (5%) women of each period. Localized infection of the cervix was detected in seven (11.7%) women. Two (3.3%) women developed cervical stenosis at 6 months after LEEP. There was no significant difference in overall complications between HIV-infected women and the control group (P = 0.24). Among 60 HIV-infected women, no statistical difference in the rate of margins involvement (P = 1.00) and complications (P = 0.85) could be demonstrated between HIV-infected women who received antiretroviral therapy and those who did not. Disease-free rate at 6 and 12 months were 97.1% and 88%, respectively. These data demonstrated that LEEP appears to be safe and effective in HIV-infected women. © 2006, Copyright the Authors.
format Journal
author C. Kietpeerakool
J. Srisomboon
P. Suprasert
C. Phongnarisorn
K. Charoenkwan
C. Cheewakriangkrai
S. Siriaree
C. Tantipalakorn
A. Pantusart
author_facet C. Kietpeerakool
J. Srisomboon
P. Suprasert
C. Phongnarisorn
K. Charoenkwan
C. Cheewakriangkrai
S. Siriaree
C. Tantipalakorn
A. Pantusart
author_sort C. Kietpeerakool
title Outcomes of loop electrosurgical excision procedure for cervical neoplasia in human immunodeficiency virus-infected women
title_short Outcomes of loop electrosurgical excision procedure for cervical neoplasia in human immunodeficiency virus-infected women
title_full Outcomes of loop electrosurgical excision procedure for cervical neoplasia in human immunodeficiency virus-infected women
title_fullStr Outcomes of loop electrosurgical excision procedure for cervical neoplasia in human immunodeficiency virus-infected women
title_full_unstemmed Outcomes of loop electrosurgical excision procedure for cervical neoplasia in human immunodeficiency virus-infected women
title_sort outcomes of loop electrosurgical excision procedure for cervical neoplasia in human immunodeficiency virus-infected women
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33745086207&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/61868
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