Curcumin inhibits WT1 gene expression in human leukemic K562 cells

• المؤلفون الرئيسيون: Songyot Anuchapreeda, Pattra Thanarattanakorn, Somjai Sittipreechacharn, Prasit Chanarat, Pornngarm Limtrakul
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Medicine; Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33644829130&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/61889

Aim: Wilms' tumor1 (WT1) gene is highly expressed in leukemic blast cells of myeloid and lymphoid origin. Thus, WT1 mRNA and protein serve as promising tumor markers for the detection of leukemia and monitoring of disease progression. The purpose of this study was to investigate the modulating...