Cell reservoirs in lymph nodes infected with HIV-1 subtype E differ from subtype B: Identification by combined in situ polymerase chain reaction and immunohistochemistry

• Main Authors: Lertlakana Bhoopat, Tat S. Rithaporn, Surapan Khunamornpong, Tanin Bhoopat, Clive R. Taylor, Paul S. Thorner
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=30944447511&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/61900
• Institution: Chiang Mai University

In Thailand, the predominant HIV subtype is E, rather than subtype B as in North America and Europe. Subtype E has the ability to replicate in vitro in Langerhans cells. We hypothesized that this cell type might constitute a reservoir for the HIV virus in infected lymph nodes. We examined lymph node...