Cytotoxicities of xanthones and cinnamate esters from Hypericum hookerianum

• Main Authors: Rujida Wilairat, Jiradej Manosroi, Aranya Manosroi, Anake Kijjoa, Maria São José Nascimento, Madalena Pinto, Artur M.S. Silva, Graham Eaton, Werner Herz
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=23644442233&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/62099
• Institution: Chiang Mai University

5-Hydroxy-2-methoxyxanthone (1), 2-hydroxy-3-methoxyxanthone (2), trans-kielcorin (3), 4-hydroxy-3-methoxyphenyl ferulate (4) and 3β-O-caffeoylbetulinic acid (5) were isolated from Hypericum hookerianum. Compounds 1-5 were tested against the growth of three human tumor cell lines, MCF-7, NCI-H460 an...